Nevoid Basal Cell Carcinoma Syndrome: <i>PTCH1</i> Mutation Profile and Expression of Genes Involved in the Hedgehog Pathway in Argentinian Patients

Nevoid Basal Cell Carcinoma Syndrome: <i>PTCH1</i> Mutation Profile and Expression of Genes Involved in the Hedgehog Pathway in Argentinian Patients

Nevoid basal cell carcinoma syndrome (NBCCS) is an autosomal dominant disorder characterized by multiple basal cell carcinomas (BCC), mainly caused by <i>PTCH1</i> gene mutations. Our current study aimed to establish (1) <i>PTCH1</i> germinal and somatic mutational status, (2...

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Bibliographic Details
Main Authors: Maria Florencia Martinez, Maria Vanesa Romano, Alfredo Pedro Martinez, Abel González, Carolina Muchnik, Fernando Miguel Stengel, Luis Daniel Mazzuoccolo, Pablo Javier Azurmendi
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Cells
Subjects:
Gorlin–Goltz syndrome
<i>PTCH1</i> mutation
Hedgehog pathway
basal cell carcinoma
Online Access:https://www.mdpi.com/2073-4409/8/2/144

Internet

https://www.mdpi.com/2073-4409/8/2/144

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