A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity

A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity

We explored the role of the adiponutrin (PNPLA3) nonsynonymous-rs738409 single nucleotide polymorphism (SNP) in genetic susceptibility to nonalcoholic fatty liver disease (NAFLD) and whether this SNP contributes to the severity of histological disease. Two hundred sixty-six individuals were evaluate...

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Bibliographic Details
Main Authors: Silvia Sookoian, Gustavo O. Castaño, Adriana L. Burgueño, Tomas Fernández Gianotti, María Soledad Rosselli, Carlos Jose Pirola
Format: Article
Language:English
Published: Elsevier 2009-10-01
Series:Journal of Lipid Research
Subjects:
SNP
genetics
replication study
PNPLA3
fatty liver
nonalcoholic steatohepatitis
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520307197

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http://www.sciencedirect.com/science/article/pii/S0022227520307197

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