Role of angiopoietin-like protein 3 in sugar-induced dyslipidemia in rhesus macaques: suppression by fish oil or RNAi[S]

Role of angiopoietin-like protein 3 in sugar-induced dyslipidemia in rhesus macaques: suppression by fish oil or RNAi[S]

Angiopoietin-like protein 3 (ANGPTL3) inhibits lipid clearance and is a promising target for managing cardiovascular disease. Here we investigated the effects of a high-sugar (high-fructose) diet on circulating ANGPTL3 concentrations in rhesus macaques. Plasma ANGPTL3 concentrations increased ∼30% t...

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Bibliographic Details
Main Authors: Andrew A. Butler, James L. Graham, Kimber L. Stanhope, So Wong, Sarah King, Andrew A. Bremer, Ronald M. Krauss, James Hamilton, Peter J. Havel
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Journal of Lipid Research
Subjects:
triglycerides
insulin resistance
apolipoproteins
lipoproteins
inflammation
C-reactive protein
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520435217

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http://www.sciencedirect.com/science/article/pii/S0022227520435217

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