In vitro and in vivo bactericidal activity of ceftazidime-avibactam against Carbapenemase–producing Klebsiella pneumoniae

In vitro and in vivo bactericidal activity of ceftazidime-avibactam against Carbapenemase–producing Klebsiella pneumoniae

Abstract Background In recent years, the incidence of carbapenem-resistant Enterobacteriaceae (CRE) infections has increased rapidly. Since the CRE strain is usually resistant to most of antimicrobial agents, patients with this infection are often accompanied by a high mortality. Therefore, it insti...

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Bibliographic Details
Main Authors: Wenxia Zhang, Yan Guo, Jiayin Li, Yiyuan Zhang, Yang Yang, Dong Dong, Demei Zhu, Ping He, Fupin Hu
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Antimicrobial Resistance and Infection Control
Subjects:
Klebsiella pneumoniae
Carbapenemase
Ceftazidime-avibactam
Aztreonam
Time-kill curve assay
Online Access:http://link.springer.com/article/10.1186/s13756-018-0435-9

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http://link.springer.com/article/10.1186/s13756-018-0435-9

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