Evolutionary modeling and prediction of non-coding RNAs in Drosophila.

We performed benchmarks of phylogenetic grammar-based ncRNA gene prediction, experimenting with eight different models of structural evolution and two different programs for genome alignment. We evaluated our models using alignments of twelve Drosophila genomes. We find that ncRNA prediction perform...

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Bibliographic Details
Main Authors: Robert K Bradley, Andrew V Uzilov, Mitchell E Skinner, Yuri R Bendaña, Lars Barquist, Ian Holmes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2721679?pdf=render