Spreading in ALS: The relative impact of upper and lower motor neuron involvement

Abstract Objective To investigate disease spread in amyotrophic lateral sclerosis (ALS), and determine the influence of lower (LMN) and upper motor neuron (UMN) involvement. Methods We assessed disease spread in ALS in 1376 consecutively studied patients, from five European centers, applying an agre...

Full description

Bibliographic Details
Main Authors: Marta Gromicho, Manuel Figueiral, Hilmi Uysal, Julian Grosskreutz, Magdalena Kuzma‐Kozakiewicz, Susana Pinto, Susanne Petri, Sara Madeira, Michael Swash, Mamede deCarvalho
Format: Article
Language:English
Published: Wiley 2020-07-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.51098