NTNG1 Modulates Cisplatin Resistance in Epithelial Ovarian Cancer Cells via the GAS6/AXL/Akt Pathway

NTNG1 Modulates Cisplatin Resistance in Epithelial Ovarian Cancer Cells via the GAS6/AXL/Akt Pathway

Cisplatin resistance is a challenge in the treatment of epithelial ovarian cancer. Here, clinical data showed that the level of netrin-G1 (NTNG1) in cisplatin-resistant cancer was higher than that in cisplatin-sensitive cancer (2.2-fold, p = 0.005); patients with a high NTNG1 level in cancer tissues...

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Bibliographic Details
Main Authors: Shanyu Fang, Yuanyuan Luo, Ying Zhang, Houmei Wang, Qianfen Liu, Xinya Li, Tinghe Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
NTNG1
cisplatin resistance
ovarian cancer
Axl
DNA repair
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.652325/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.652325/full

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