The SET-domain protein SUVR5 mediates H3K9me2 deposition and silencing at stimulus response genes in a DNA methylation-independent manner.

In eukaryotic cells, environmental and developmental signals alter chromatin structure and modulate gene expression. Heterochromatin constitutes the transcriptionally inactive state of the genome and in plants and mammals is generally characterized by DNA methylation and histone modifications such a...

Full description

Bibliographic Details
Main Authors: Elena Caro, Hume Stroud, Maxim V C Greenberg, Yana V Bernatavichute, Suhua Feng, Martin Groth, Ajay A Vashisht, James Wohlschlegel, Steve E Jacobsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3469426?pdf=render