Effect of bosentan upon pulmonary hypertension in chronic obstructive pulmonary disease

Background: Pulmonary hypertension (PH) in chronic obstructive pulmonary disease (COPD) is mainly determined by hypoxemia under respiratory failure by means of the functional hypoxemic vasoconstrictor response. Organic changes of vessels, pulmonary vascular remodelling, is gaining increasing relevan...

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Bibliographic Details
Main Authors: Giuseppe Valerio, Pierluigi Bracciale, Anna Grazia D'Agostino
Format: Article
Language:English
Published: SAGE Publishing 2009-02-01
Series:Therapeutic Advances in Respiratory Disease
Online Access:https://doi.org/10.1177/1753465808103499