CONVERGENT SYNTHESIS AND EVALUATION OF 18F-LABELED AZULENIC COX2 PROBES FOR CANCER IMAGING

CONVERGENT SYNTHESIS AND EVALUATION OF 18F-LABELED AZULENIC COX2 PROBES FOR CANCER IMAGING

The overall objectives of this research are to (i) develop azulene-based PET probes and (ii) image COX2 as a potential biomarker of breast cancer. Several lines of research have demonstrated that COX2 is overexpressed in breast cancer and that its presence correlates with poor prognoses. While other...

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Bibliographic Details
Main Authors: Donald D. Nolting, Michael eNickels, Mohammed N. Tantawy, James Y. H. Yu, Jingping eXie, Todd E. Peterson, Brenda A. Crews, Larry eMarnett, John C. Gore, Wellington ePham
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-01-01
Series:Frontiers in Oncology
Subjects:
Molecular Imaging
Cancer
PET
COX2
Azulene
xenograft tumor
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00207/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00207/full

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