MrkH, a novel c-di-GMP-dependent transcriptional activator, controls Klebsiella pneumoniae biofilm formation by regulating type 3 fimbriae expression.

MrkH, a novel c-di-GMP-dependent transcriptional activator, controls Klebsiella pneumoniae biofilm formation by regulating type 3 fimbriae expression.

Klebsiella pneumoniae causes significant morbidity and mortality worldwide, particularly amongst hospitalized individuals. The principle mechanism for pathogenesis in hospital environments involves the formation of biofilms, primarily on implanted medical devices. In this study, we constructed a tra...

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Bibliographic Details
Main Authors: Jonathan J Wilksch, Ji Yang, Abigail Clements, Jacinta L Gabbe, Kirsty R Short, Hanwei Cao, Rosalia Cavaliere, Catherine E James, Cynthia B Whitchurch, Mark A Schembri, Mary L C Chuah, Zhao-Xun Liang, Odilia L Wijburg, Adam W Jenney, Trevor Lithgow, Richard A Strugnell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-08-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21901098/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21901098/?tool=EBI

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