The Role of BAFF-R Signaling in the Growth of Primary Central Nervous System Lymphoma

The Role of BAFF-R Signaling in the Growth of Primary Central Nervous System Lymphoma

Primary CNS lymphoma (PCNSL) is an aggressive brain tumor. Despite improvements in therapeutic algorithms, long-term survival remains rare, illustrating an urgent need for novel therapeutic targets. BAFF-R is a pro-survival receptor expressed on most malignant B cells, including PCNSL. To date, its...

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Bibliographic Details
Main Authors: Xiaolan Zhou, Matthias Mulazzani, Iven-Alex von Mücke-Heim, Sigrid Langer, Wenlong Zhang, Hellen Ishikawa-Ankerhold, Martin Dreyling, Andreas Straube, Louisa von Baumgarten
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Oncology
Subjects:
PCNSL
CRISPR-Cas9
intravital microscopy
brain tumor
knockout
BAFF-R
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00682/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.00682/full

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