The Role of BAFF-R Signaling in the Growth of Primary Central Nervous System Lymphoma
Primary CNS lymphoma (PCNSL) is an aggressive brain tumor. Despite improvements in therapeutic algorithms, long-term survival remains rare, illustrating an urgent need for novel therapeutic targets. BAFF-R is a pro-survival receptor expressed on most malignant B cells, including PCNSL. To date, its...
Main Authors: | Xiaolan Zhou, Matthias Mulazzani, Iven-Alex von Mücke-Heim, Sigrid Langer, Wenlong Zhang, Hellen Ishikawa-Ankerhold, Martin Dreyling, Andreas Straube, Louisa von Baumgarten |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-05-01
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Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fonc.2020.00682/full |
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