Neuroblastoma-secreted exosomes carrying miR‐375 promote osteogenic differentiation of bone-marrow mesenchymal stromal cells

Neuroblastoma-secreted exosomes carrying miR‐375 promote osteogenic differentiation of bone-marrow mesenchymal stromal cells

Bone marrow (BM) is the major target organ for neuroblastoma (NB) metastasis and its involvement is associated with poor outcome. Yet, the mechanism by which NB cells invade BM is largely unknown. Tumour microenvironment represents a key element in tumour progression and mesenchymal stromal cells (M...

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Bibliographic Details
Main Authors: Marta Colletti, Luigi Tomao, Angela Galardi, Alessandro Paolini, Virginia Di Paolo, Cristiano De Stefanis, Paolo Mascio, Francesca Nazio, Stefania Petrini, Aurora Castellano, Ida Russo, Roberta Caruso, Simone Piga, Rita De Vito, Luisa Pascucci, Hector Peinado, Andrea Masotti, Franco Locatelli, Angela Di Giannatale
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Journal of Extracellular Vesicles
Subjects:
exosomes
mir-375
mscs
bone-marrow metastasis
microenvironment
Online Access:http://dx.doi.org/10.1080/20013078.2020.1774144

Internet

http://dx.doi.org/10.1080/20013078.2020.1774144

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