The Effect of CDK6 Expression on DNA Methylation and DNMT3B Regulation

Summary: CDK6 is frequently overexpressed in various cancer types and functions as a positive regulator of the cell cycle and as a coregulator of gene transcription. We provide evidence that CDK6 is involved in the process of DNA methylation, at least in ALL. We observe a positive correlation of CDK...

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Bibliographic Details
Main Authors: Gerwin Heller, Sofie Nebenfuehr, Florian Bellutti, Huriye Ünal, Markus Zojer, Lisa Scheiblecker, Veronika Sexl, Karoline Kollmann
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422030794X