Alzheimer’s Disease: A Molecular View of β-Amyloid Induced Morbific Events

Alzheimer’s Disease: A Molecular View of β-Amyloid Induced Morbific Events

Amyloid-β (Aβ) is a dynamic peptide of Alzheimer’s disease (AD) which accelerates the disease progression. At the cell membrane and cell compartments, the amyloid precursor protein (APP) undergoes amyloidogenic cleavage by β- and γ-secretases and engenders the Aβ. In addition, externally produced Aβ...

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Bibliographic Details
Main Authors: Rajmohamed Mohamed Asik, Natarajan Suganthy, Mohamed Asik Aarifa, Arvind Kumar, Krisztián Szigeti, Domokos Mathe, Balázs Gulyás, Govindaraju Archunan, Parasuraman Padmanabhan
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Biomedicines
Subjects:
amyloid beta
Alzheimer’s disease
inflammation
gene regulation
organelle dysfunction
Online Access:https://www.mdpi.com/2227-9059/9/9/1126

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https://www.mdpi.com/2227-9059/9/9/1126

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