Identifying Pseudomonas syringae Type III Secreted Effector Function via a Yeast Genomic Screen

Identifying Pseudomonas syringae Type III Secreted Effector Function via a Yeast Genomic Screen

Gram-negative bacterial pathogens inject type III secreted effectors (T3SEs) directly into host cells to promote pathogen fitness by manipulating host cellular processes. Despite their crucial role in promoting virulence, relatively few T3SEs have well-characterized enzymatic activities or host targ...

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Bibliographic Details
Main Authors: Amy Huei-Yi Lee, D. Patrick Bastedo, Ji-Young Youn, Timothy Lo, Maggie A. Middleton, Inga Kireeva, Jee Yeon Lee, Sara Sharifpoor, Anastasia Baryshnikova, Jianfeng Zhang, Pauline W. Wang, Sergio G. Peisajovich, Michael Constanzo, Brenda J. Andrews, Charles M. Boone, Darrell Desveaux, David S. Guttman
Format: Article
Language:English
Published: Oxford University Press 2019-02-01
Series:G3: Genes, Genomes, Genetics
Subjects:
Pseudomonas syringae
Type III secreted effector
Pathogenic Genetic Array
Yeast screen
Pathogen-host interactions
HopZ1
Kinesin
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.118.200877

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http://g3journal.org/lookup/doi/10.1534/g3.118.200877

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