Differentiation-inducing effect of piperitenone oxide, a fragrant ingredient of spearmint (Mentha spicata), but not carvone and menthol, against human colon cancer cells

Differentiation-inducing effect of piperitenone oxide, a fragrant ingredient of spearmint (Mentha spicata), but not carvone and menthol, against human colon cancer cells

The n-hexane extract from spearmint (Mentha spicata) leaves was purified via a bioassay-guided fractionation scheme, which was based on the induction of differentiation in a RCM-1 human colon cancer cell line. One of the criteria of a differentiation marker is the formation of ducts determined visua...

Full description

Bibliographic Details
Main Authors: Yasushi Nakamura, Yuki Hasegawa, Koji Shirota, Noboru Suetome, Takako Nakamura, Mullika Traidej Chomnawang, Krit Thirapanmethee, Piyatip Khuntayaporn, Panida Boonyaritthongchai, Chalermchai Wongs-Aree, Shigehisa Okamoto, Tomoaki Shigeta, Tomoaki Matsuo, Eun Young Park, Kenji Sato
Format: Article
Language:English
Published: Elsevier 2014-05-01
Series:Journal of Functional Foods
Subjects:
Spearmint
Terpenoid
Cancer
Colon
Differentiation
Mentha spicata
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464614000772

Internet

http://www.sciencedirect.com/science/article/pii/S1756464614000772

Similar Items