Influence of parameter perturbations on the reachability of therapeutic target in systems with switchings

Abstract Background Examination of physiological processes and the influences of the drugs on them can be efficiently supported by mathematical modeling. One of the biggest problems is related to the exact fitting of the parameters of a model. Conditions inside the organism change dynamically, so th...

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Bibliographic Details
Main Authors: Magdalena Ochab, Krzysztof Puszynski, Andrzej Swierniak
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BioMedical Engineering OnLine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12938-017-0360-9