ARTEMIS stabilizes the genome and modulates proliferative responses in multipotent mesenchymal cells

<p>Abstract</p> <p>Background</p> <p>Unrepaired DNA double-stranded breaks (DSBs) cause chromosomal rearrangements, loss of genetic information, neoplastic transformation or cell death. The nonhomologous end joining (NHEJ) pathway, catalyzing sequence-independent direct...

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Bibliographic Details
Main Authors: Tompkins Kathleen, Donghia Nina M, Maas Sarah A, Foreman Oded, Mills Kevin D
Format: Article
Language:English
Published: BMC 2010-10-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/8/132