Reassessing the Role of the Active TGF-β1 as a Biomarker in Systemic Sclerosis: Association of Serum Levels with Clinical Manifestations

Reassessing the Role of the Active TGF-β1 as a Biomarker in Systemic Sclerosis: Association of Serum Levels with Clinical Manifestations

Objective. To determine active TGF-β1 (aTGF-β1) levels in serum, skin, and peripheral blood mononuclear cell (PBMC) culture supernatants and to understand their associations with clinical parameters in systemic sclerosis (SSc) patients. Methods. We evaluated serum samples from 56 SSc patients and 24...

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Main Authors: Andréa Tavares Dantas, Sayonara Maria Calado Gonçalves, Anderson Rodrigues de Almeida, Rafaela Silva Guimarães Gonçalves, Maria Clara Pinheiro Duarte Sampaio, Kamila de Melo Vilar, Michelly Cristiny Pereira, Moacyr Jesus Barreto de Melo Rêgo, Ivan da Rocha Pitta, Claudia Diniz Lopes Marques, Angela Luzia Branco Pinto Duarte, Maira Galdino da Rocha Pitta
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2016/6064830

Internet

http://dx.doi.org/10.1155/2016/6064830

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