Evolution of the Sinus Venosus from Fish to Human

The sinus venosus, the cardiac chamber upstream of the (right) atrium, is a severely underinvestigated structure. Yet, its myocardium harbors the cardiac pacemaker in all vertebrates. In human, ectopic pacemaking and subsequent pathologies may originate from sinus venosus-derived myocardium surround...

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Bibliographic Details
Main Authors: Bjarke Jensen, Bastiaan J. D. Boukens, Tobias Wang, Antoon F. M. Moorman, Vincent M. Christoffels
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
Online Access:http://www.mdpi.com/2308-3425/1/1/14