Thioredoxin-1 protects against neutrophilic inflammation and emphysema progression in a mouse model of chronic obstructive pulmonary disease exacerbation.

Thioredoxin-1 protects against neutrophilic inflammation and emphysema progression in a mouse model of chronic obstructive pulmonary disease exacerbation.

BACKGROUND: Exacerbations of chronic obstructive pulmonary disease (COPD) are characterized by acute enhancement of airway neutrophilic inflammation under oxidative stress and can be involved in emphysema progression. However, pharmacotherapy against the neutrophilic inflammation and emphysema progr...

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Bibliographic Details
Main Authors: Naoya Tanabe, Yuma Hoshino, Satoshi Marumo, Hirofumi Kiyokawa, Susumu Sato, Daisuke Kinose, Kazuko Uno, Shigeo Muro, Toyohiro Hirai, Junji Yodoi, Michiaki Mishima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3823967?pdf=render

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http://europepmc.org/articles/PMC3823967?pdf=render

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