SOX2 and SOX2-MYC Reprogramming Process of Fibroblasts to the Neural Stem Cells Compromised by Senescence.

SOX2 and SOX2-MYC Reprogramming Process of Fibroblasts to the Neural Stem Cells Compromised by Senescence.

Tumorigenic potential of induced pluripotent stem cells (iPSCs) infiltrating population of induced neural stem cells (iNSCs) generated from iPSCs may limit their medical applications. To overcome such a difficulty, direct reprogramming of adult somatic cells into iNSCs was proposed. The aim of this...

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Bibliographic Details
Main Authors: Marta Winiecka-Klimek, Maciej Smolarz, Maciej P Walczak, Jolanta Zieba, Krystyna Hulas-Bigoszewska, Blazej Kmieciak, Sylwester Piaskowski, Piotr Rieske, Dawid P Grzela, Ewelina Stoczynska-Fidelus
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4633175?pdf=render

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http://europepmc.org/articles/PMC4633175?pdf=render

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