Formulation, Optimization and Characterization of Chitosan Monodisperse Microparticles for Sustained Delivery of Hydrochlorothiazide HCl

Background: Hydrochlorothiazide HCl (HCTZ) is first line medication in the management of hypertension, however its poor solubility and GI irritation warrants long term application. The aim of present study was to prepare hydrochlorothiazide HCl (HCTZ) loaded monodisperse microparticles of chitosan (...

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Bibliographic Details
Main Authors: Jahanzeb Mudassir, Aruba Khan Sherwani, Amjad Hussain, Nasir Abbas, Muhammad sohail Arshad
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2020-09-01
Series:Pharmaceutical Sciences
Subjects:
Online Access:https://ps.tbzmed.ac.ir/PDF/ps-26-306.pdf