Formulation, Optimization and Characterization of Chitosan Monodisperse Microparticles for Sustained Delivery of Hydrochlorothiazide HCl
Background: Hydrochlorothiazide HCl (HCTZ) is first line medication in the management of hypertension, however its poor solubility and GI irritation warrants long term application. The aim of present study was to prepare hydrochlorothiazide HCl (HCTZ) loaded monodisperse microparticles of chitosan (...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Tabriz University of Medical Sciences
2020-09-01
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Series: | Pharmaceutical Sciences |
Subjects: | |
Online Access: | https://ps.tbzmed.ac.ir/PDF/ps-26-306.pdf |