Developmental Pathways Pervade Stem Cell Responses to Evolving Extracellular Matrices of 3D Bioprinted Microenvironments

Developmental studies and 3D in vitro model systems show that the production and engagement of extracellular matrix (ECM) often precede stem cell differentiation. Yet, unclear is how the ECM triggers signaling events in sequence to accommodate multistep process characteristic of differentiation. Her...

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Bibliographic Details
Main Authors: Quyen A. Tran, Visar Ajeti, Brian T. Freeman, Paul J. Campagnola, Brenda M. Ogle
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2018/4809673