Caco-2 cell acquisition of dietary iron(III) invokes a nanoparticulate endocytic pathway.

Caco-2 cell acquisition of dietary iron(III) invokes a nanoparticulate endocytic pathway.

Dietary non-heme iron contains ferrous [Fe(II)] and ferric [Fe(III)] iron fractions and the latter should hydrolyze, forming Fe(III) oxo-hydroxide particles, on passing from the acidic stomach to less acidic duodenum. Using conditions to mimic the in vivo hydrolytic environment we confirmed the form...

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Bibliographic Details
Main Authors: Dora I A Pereira, Bianca I Mergler, Nuno Faria, Sylvaine F A Bruggraber, Mohamad F Aslam, Lynsey K Poots, Laura Prassmayer, Bo Lönnerdal, Andy P Brown, Jonathan J Powell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3836913?pdf=render

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http://europepmc.org/articles/PMC3836913?pdf=render

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