Exosomal circPACRGL promotes progression of colorectal cancer via the miR-142-3p/miR-506-3p- TGF-β1 axis

Exosomal circPACRGL promotes progression of colorectal cancer via the miR-142-3p/miR-506-3p- TGF-β1 axis

Abstract Background Colorectal cancer (CRC) is the leading cause of cancer-related death worldwide. Exosome shave emerged as crucial regulators of intercellular communication and that abundant Circular RNAs (circRNAs) are enriched within exosomes. CircRNAs are novel members of noncoding RNAs regulat...

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Bibliographic Details
Main Authors: Anquan Shang, Chenzheng Gu, Weiwei Wang, Xuan Wang, Junjun Sun, Bingjie Zeng, Chen Chen, Wenjing Chang, Yili Ping, Ping Ji, Junlu Wu, Wenqiang Quan, Yiwen Yao, Yongxin Zhou, Zujun Sun, Dong Li
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Molecular Cancer
Subjects:
Colorectal cancer
Exosome
circPACRGL
miR-142-3p
miR-506-3p
TGF-β1
Online Access:http://link.springer.com/article/10.1186/s12943-020-01235-0

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http://link.springer.com/article/10.1186/s12943-020-01235-0

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