Conserved Streptococcus pneumoniae spirosomes suggest a single type of transformation pilus in competence.

The success of S. pneumoniae as a major human pathogen is largely due to its remarkable genomic plasticity, allowing efficient escape from antimicrobials action and host immune response. Natural transformation, or the active uptake and chromosomal integration of exogenous DNA during the transitory d...

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Bibliographic Details
Main Authors: Raphaël Laurenceau, Petya V Krasteva, Amy Diallo, Sahra Ouarti, Magalie Duchateau, Christian Malosse, Julia Chamot-Rooke, Rémi Fronzes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-04-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1004835