The Slow-Releasing and Mitochondria-Targeted Hydrogen Sulfide (H<sub>2</sub>S) Delivery Molecule AP39 Induces Brain Tolerance to Ischemia

The Slow-Releasing and Mitochondria-Targeted Hydrogen Sulfide (H<sub>2</sub>S) Delivery Molecule AP39 Induces Brain Tolerance to Ischemia

Ischemic stroke is the third leading cause of death in the world, which accounts for almost 12% of the total deaths worldwide. Despite decades of research, the available and effective pharmacotherapy is limited. Some evidence underlines the beneficial properties of hydrogen sulfide (H<sub>2<...

Full description

Bibliographic Details
Main Authors: Bartosz Pomierny, Weronika Krzyżanowska, Jakub Jurczyk, Alicja Skórkowska, Beata Strach, Małgorzata Szafarz, Katarzyna Przejczowska-Pomierny, Roberta Torregrossa, Matthew Whiteman, Monika Marcinkowska, Joanna Pera, Bogusława Budziszewska
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
brain ischemia
hydrogen sulfide
AP39
brain preconditioning
neuroinflammation
mitochondrial targeting
Online Access:https://www.mdpi.com/1422-0067/22/15/7816

Internet

https://www.mdpi.com/1422-0067/22/15/7816

Similar Items