RhoA: A therapeutic target for chronic myeloid leukemia

RhoA: A therapeutic target for chronic myeloid leukemia

<p>Abstract</p> <p>Background</p> <p>Chronic Myeloid Leukemia (CML) is a malignant pluripotent stem cells disorder of myeloid cells. In CML patients, polymorphonuclear leukocytes (PMNL) the terminally differentiated cells of myeloid series exhibit defects in several act...

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Bibliographic Details
Main Authors: Molli Poonam R, Pradhan Madhura B, Advani Suresh H, Naik Nishigandha R
Format: Article
Language:English
Published: BMC 2012-03-01
Series:Molecular Cancer
Subjects:
Chronic Myeloid Leukemia (CML)
Actin
RhoGTPases
Polymorphonuclear leukocytes (PMNL)
n-formyl-methionyl-leucyl-phenylalanine (fMLP)
Signal transduction
Online Access:http://www.molecular-cancer.com/content/11/1/16

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http://www.molecular-cancer.com/content/11/1/16

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