Histone Deacetylase Inhibitor Induced Radiation Sensitization Effects on Human Cancer Cells after Photon and Hadron Radiation Exposure

Suberoylanilide hydroxamic acid (SAHA) is a histone deacetylase inhibitor, which has been widely utilized throughout the cancer research field. SAHA-induced radiosensitization in normal human fibroblasts AG1522 and lung carcinoma cells A549 were evaluated with a combination of γ-rays, proton, and ca...

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Bibliographic Details
Main Authors: Ariungerel Gerelchuluun, Junko Maeda, Eri Manabe, Colleen A. Brents, Takeji Sakae, Akira Fujimori, David J. Chen, Koji Tsuboi, Takamitsu A. Kato
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/19/2/496