M860, a Monoclonal Antibody against Human Lactoferrin, Enhances Tumoricidal Activity of Low Dosage Lactoferrin via Granzyme B Induction

M860, a Monoclonal Antibody against Human Lactoferrin, Enhances Tumoricidal Activity of Low Dosage Lactoferrin via Granzyme B Induction

Lactoferrin (LF) is a soluble glycoprotein of the transferring family found in most biological fluids, functioning as a major first line defense molecule against infection in mammals. It also shows certain anti-tumor activity, but its clinical application in tumor therapy is limited because high dos...

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Bibliographic Details
Main Authors: Ya Li, Jie Li, Zheng Gong, Xiao-Hua Pan, Zi-Han Ma, Shu-Yan Ma, Hong-Min Wang, Hong-Liang Dong, Fang-Yuan Gong, Xiao-Ming Gao
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Molecules
Subjects:
lactoferrin immune-complex
granzyme b
monocytes
tumoricidal activity
Online Access:https://www.mdpi.com/1420-3049/24/20/3640

Internet

https://www.mdpi.com/1420-3049/24/20/3640

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