17β-estradiol regulates the expression of apolipoprotein M through estrogen receptor α-specific binding motif in its promoter

17β-estradiol regulates the expression of apolipoprotein M through estrogen receptor α-specific binding motif in its promoter

Abstract Background We have previously demonstrated that estrogen could significantly enhance expression of apolipoprotein M (apoM), whereas the molecular basis of its mechanism is not fully elucidated yet. To further investigate the mechanism behind the estrogen induced up-regulation of apoM expres...

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Bibliographic Details
Main Authors: Jiang Wei, Yang Yu, Guang-hua Luo, Yue-hua Feng, Yuan-ping Shi, Jun Zhang, Qin-feng Mu, Miao-mei Yu, Li-li Pan, Maria Berggren-Söderlund, Peter Nilsson-Ehle, Xiao-ying Zhang, Ning Xu
Format: Article
Language:English
Published: BMC 2017-03-01
Series:Lipids in Health and Disease
Subjects:
Estrogen receptor alpha
Apolipoprotein M
Estrogen responsive element
Electrophoretic mobility shift assay (EMSA)
Chromatin Immunoprecipitation (ChIP) assay
Online Access:http://link.springer.com/article/10.1186/s12944-017-0458-x

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http://link.springer.com/article/10.1186/s12944-017-0458-x

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