Brain and Plasma Riluzole Pharmacokinetics: Effect of Minocycline Combination

PURPOSE: amyotrophic lateral sclerosis is a fatal neurodegenerative disease characterized by the loss of motorneurons. The only drug approved is riluzole. Minocycline is an antibiotic with numerous neuroprotective properties. riluzole and minocycline were given to an animal model of ALS and had bene...

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Bibliographic Details
Main Authors: Aline Milane, Lionel Tortolano, Christine Fernandez, Gilbert Bensimon, Vincent Meininger, Robert Farinotti
Format: Article
Language:English
Published: Canadian Society for Pharmaceutical Sciences 2009-08-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/4596