The ribosome biogenesis factor Nol11 is required for optimal rDNA transcription and craniofacial development in Xenopus.

The production of ribosomes is ubiquitous and fundamental to life. As such, it is surprising that defects in ribosome biogenesis underlie a growing number of symptomatically distinct inherited disorders, collectively called ribosomopathies. We previously determined that the nucleolar protein, NOL11,...

Full description

Bibliographic Details
Main Authors: John N Griffin, Samuel B Sondalle, Florencia Del Viso, Susan J Baserga, Mustafa K Khokha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4354908?pdf=render