Longitudinal Morphological and Functional Assessment of RGC Neurodegeneration After Optic Nerve Crush in Mouse

The mouse optic nerve crush (ONC) model has been widely used to study optic neuropathies and central nervous system (CNS) axon injury and repair. Previous histological studies of retinal ganglion cell (RGC) somata in retina and axons in ON demonstrate significant neurodegeneration after ONC, but lon...

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Bibliographic Details
Main Authors: Liang Li, Haoliang Huang, Fang Fang, Liang Liu, Yang Sun, Yang Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
RGC
ON
OCT
SLO
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00109/full