IL-33 promotes ICAM-1 expression via NF-kB in murine mast cells

Background: IL-33, a member of the IL-1 cytokine family, binds to heterodimeric receptors ST2 and IL-1 receptor accessory protein, and activates Th2-type immune responses. The signals from the ST2 receptor are mediated by the two major pathways, including AP-1 and NF-κB molecules. The present study...

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Bibliographic Details
Main Authors: Takafumi Numata, Tomonobu Ito, Tatsuo Maeda, Chizu Egusa, Ryoji Tsuboi
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Allergology International
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015002002