Predominant overexpression of CD25/FOXP3, IFN-γ, and suppressive cytokines in high-grade lesion samples infected with human papillomavirus

Predominant overexpression of CD25/FOXP3, IFN-γ, and suppressive cytokines in high-grade lesion samples infected with human papillomavirus

ABSTRACT Introduction: Human papillomavirus (HPV) persistent infection is the leading cause of cervical cancer and its precursor lesions, and the inappropriate immune response is among the factors that contribute to viral persistence. This may be influenced by regulatory T (Treg) cells and the prod...

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Bibliographic Details
Main Authors: Camila M. Bonin, Cacilda T. J. Padovani, Alda Maria T. Ferreira, Leandro S. Ávila, Ana Paula Machado, Thiago T. M. Prata, Carlos Eurico S. Fernandes, Inês Aparecida Tozetti
Format: Article
Language:English
Published: Sociedade Brasileira de Patologia Clínica
Series:Jornal Brasileiro de Patologia e Medicina Laboratorial
Subjects:
immunohistochemistry
immunomodulation
papillomavirus infections
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442017000100053&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442017000100053&lng=en&tlng=en

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