A novel strategy for D-psicose and lipase co-production using a co-culture system of engineered Bacillus subtilis and Escherichia coli and bioprocess analysis using metabolomics
Highlights Co-cultivation was firstly carried out for the co-production of D-psicose and lipase. The carbon source glucose and fructose were fully utilized during co-culture. The yield of D- psicose was 11.70 g/L, and the conversion rate reached 69.54%. Self-induced expression of lipase was realized...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2021-08-01
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| Series: | Bioresources and Bioprocessing |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40643-021-00429-8 |