Induction of Chimerism in Mice Using Human MHC Class I-Mismatched Hoechst 33342 Side Population Donor Stem Cells

A population of Hoechst 33342-stained cells, termed side population (SP) cells, can reconstitute the hematopoietic system of syngeneic mice. This study examined whether limiting numbers of SP cells can repopulate mice across a xenogeneic MHC class I barrier. SP cells were isolated from HLA.B7 and HL...

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Bibliographic Details
Main Authors: John D. Jackson, Guimei Zhou, Charles A. Kuszynski, Jin Cai, Ira J. Fox M.D.
Format: Article
Language:English
Published: SAGE Publishing 2002-11-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000002783985224