TRAF1 suppresses antifungal immunity through CXCL1-mediated neutrophil recruitment during Candida albicans intradermal infection

TRAF1 suppresses antifungal immunity through CXCL1-mediated neutrophil recruitment during Candida albicans intradermal infection

Abstract Background Candida albicans is the most common opportunistic human fungal pathogen. The chemokine ligand CXCL1 plays a protective role in fungal infection through the recruitment of neutrophils. TRAF1 (tumor necrosis factor-associated factor 1) can be highly induced by proinflammatory stimu...

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Bibliographic Details
Main Authors: Wenjuan Bai, Qingqing Wang, Zihou Deng, Tiantian Li, Hui Xiao, Zhiyuan Wu
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Cell Communication and Signaling
Subjects:
CXCL1
TRAF1
C. albicans
Skin infection
Neutrophil
Online Access:http://link.springer.com/article/10.1186/s12964-020-00532-x

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http://link.springer.com/article/10.1186/s12964-020-00532-x

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