Transcription factors bind thousands of active and inactive regions in the Drosophila blastoderm.

Transcription factors bind thousands of active and inactive regions in the Drosophila blastoderm.

Identifying the genomic regions bound by sequence-specific regulatory factors is central both to deciphering the complex DNA cis-regulatory code that controls transcription in metazoans and to determining the range of genes that shape animal morphogenesis. We used whole-genome tiling arrays to map s...

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Bibliographic Details
Main Authors: Xiao-yong Li, Stewart MacArthur, Richard Bourgon, David Nix, Daniel A Pollard, Venky N Iyer, Aaron Hechmer, Lisa Simirenko, Mark Stapleton, Cris L Luengo Hendriks, Hou Cheng Chu, Nobuo Ogawa, William Inwood, Victor Sementchenko, Amy Beaton, Richard Weiszmann, Susan E Celniker, David W Knowles, Tom Gingeras, Terence P Speed, Michael B Eisen, Mark D Biggin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-02-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2235902?pdf=render

Internet

http://europepmc.org/articles/PMC2235902?pdf=render

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