Is the A-Chain the Engine That Drives the Diversity of C1q Functions? Revisiting Its Unique Structure

The immunopathological functions associated with human C1q are still growing in terms of novelty, diversity, and pathologic relevance. It is, therefore, not surprising that C1q is being recognized as an important molecular bridge between innate and adaptive immunity. The secret of this functional di...

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Bibliographic Details
Main Authors: Berhane Ghebrehiwet, Evelyn Kandov, Uday Kishore, Ellinor I. B. Peerschke
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Immunology
Subjects:
C1q
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00162/full