Adaptor protein LNK promotes anaplastic thyroid carcinoma cell growth via 14-3-3 ε/γ binding

Adaptor protein LNK promotes anaplastic thyroid carcinoma cell growth via 14-3-3 ε/γ binding

Abstract Background Rapid progression contributes to treatment failure in anaplastic thyroid carcinoma (ATC) patients. In a preliminary study, we demonstrated that some hematopoietic factors may be involved in the progression of ATC. The adaptor protein LNK, which is a negative regulator of hematopo...

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Bibliographic Details
Main Authors: Zhao-Ming Zhong, Xue Chen, Xiao Qi, Xue-Min Wang, Chun-Yan Li, Ru-Jia Qin, Shi-Qi Wang, Jin Liang, Mu-Sheng Zeng, Chuan-Zheng Sun
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Cancer Cell International
Subjects:
Adaptor protein
Anaplastic thyroid carcinoma
Cell growth
LNK
14-3-3 ε/γ
Online Access:https://doi.org/10.1186/s12935-019-1090-9

Internet

https://doi.org/10.1186/s12935-019-1090-9

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