Distinguishing naive‐ from memory‐derived human B cells during acute responses

Abstract Objectives A fundamental question in influenza research is whether antibody titre decline upon successive exposure to variant strains is consequent to recall of cross‐reactive memory B cells that competitively inhibit naive B‐cell responses. In connection, it is not clear whether naive and...

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Bibliographic Details
Main Authors: Maria Auladell, Thi Ho Nguyen, Beatriz Garcillán, Fabienne Mackay, Katherine Kedzierska, Annette Fox
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Clinical & Translational Immunology
Subjects:
TLR
Online Access:https://doi.org/10.1002/cti2.1090