Engineering of Streptomyces lividans for heterologous expression of secondary metabolite gene clusters

Abstract Background Heterologous expression of secondary metabolite gene clusters is used to achieve increased production of desired compounds, activate cryptic gene clusters, manipulate clusters from genetically unamenable strains, obtain natural products from uncultivable species, create new unnat...

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Bibliographic Details
Main Authors: Yousra Ahmed, Yuriy Rebets, Marta Rodríguez Estévez, Josef Zapp, Maksym Myronovskyi, Andriy Luzhetskyy
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Microbial Cell Factories
Subjects:
Online Access:https://doi.org/10.1186/s12934-020-1277-8