Somatic mutations favorable to patient survival are predominant in ovarian carcinomas.

Somatic mutation accumulation is a major cause of abnormal cell growth. However, some mutations in cancer cells may be deleterious to the survival and proliferation of the cancer cells, thus offering a protective effect to the patients. We investigated this hypothesis via a unique analysis of the cl...

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Bibliographic Details
Main Authors: Wensheng Zhang, Andrea Edwards, Erik Flemington, Kun Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4229214?pdf=render