A cohesin-independent role for NIPBL at promoters provides insights in CdLS.

The cohesin complex is crucial for chromosome segregation during mitosis and has recently also been implicated in transcriptional regulation and chromatin architecture. The NIPBL protein is required for the loading of cohesin onto chromatin, but how and where cohesin is loaded in vertebrate cells is...

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Bibliographic Details
Main Authors: Jessica Zuin, Vedran Franke, Wilfred F J van Ijcken, Antoine van der Sloot, Ian D Krantz, Michael I J A van der Reijden, Ryuichiro Nakato, Boris Lenhard, Kerstin S Wendt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3923681?pdf=render