Genetic Polymorphisms and In Silico Mutagenesis Analyses of CYP2C9, CYP2D6, and CYPOR Genes in the Pakistani Population

Genetic Polymorphisms and In Silico Mutagenesis Analyses of CYP2C9, CYP2D6, and CYPOR Genes in the Pakistani Population

Diverse distributions of pharmacogenetically relevant variants of highly polymorphic CYP2C9, CYP2D6 and CYPOR genes are responsible for some varied drug responses observed across human populations. There is limited data available regarding the pharmacogenetic polymorphisms and frequency distribution...

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Bibliographic Details
Main Authors: Shabbir Ahmed, Jie Zhou, Zhan Zhou, Shu-Qing Chen
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Genes
Subjects:
pharmacogenomics
drug-metabolizing enzymes
polymorphism
alleles frequencies
in silico mutagenesis
Pakistani population
Online Access:http://www.mdpi.com/2073-4425/9/10/514

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http://www.mdpi.com/2073-4425/9/10/514

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